Anomaly detection in gene expression via stochastic models of gene regulatory networks

BMC Genomics

Table 1 Parameters of stochastic gene expression model

Parameters		Values	References
Transcription initiation	λ ₂	0.0025 sec^-1	[16, 22]
Translation initiation	λ ₃	0.0612 sec^-1	[14, 16]
mRNA degradation	γ ₂	0.00578 sec^-1	[16]
Monomer degradation	γ ₃	0.00077 sec^-1	[16, 17]
Dimer degradation	γ ₄	0.00057 sec^-1	[16, 17]
Dimer association	k _{a 1}	0.1	[17]
Dimer dissociation	k _{d 1}	0.01	[17]
DNA-protein association	k _{a 2}	0.189	[18]
DNA-protein dissociation	k _{d 2}	0.0157	[18]
Burst size	b	10	[14, 16]
Accumulation time of proteins	Δt	0.1	[11]

ISSN: 1471-2164