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Table 3 Top ten genes found differentially up- or down-regulated after LPS or PMA/ionomycin stimulation

From: Transcriptome analysis of porcine PBMCs after in vitro stimulation by LPS or PMA/ionomycin using an expression array targeting the pig immune response

 

LPS stimulation

PMA/ionomycin stimulation

 

Genes

Clusters2

Fold change

Genes

Clusters2

Fold change

Up-regulation

SAA1

C4

26.84

IL2

No3

9.96

 

IL8

C3

23.96

HSP90AB1

C6

8.49

 

CCL2

C4

13.36

NPM1

C6

8.21

 

S100A9

C3

13.33

CD69

No3

6.87

 

CXCL5

C4

12.42

TNFRSF9

No3

6.62

 

S100A12

No3

10.92

NPM3

C6

6.61

 

CXCL3

No3

9.55

HSPD1

C6

6.51

 

CXCL2

No3

7.96

GAPDH

C6

6.20

 

CCL8

No3

7.36

RPS2

C6

5.31

 

SOD2

C6

5.85

RAN

C6

5.31

Down-regulation

LYZ1

C1

-8.59

THBS1

C2

-65.98

 

FN11

C1

-7.57

FOLR11

C1

-19.74

 

SLA-DRB1

C8

-3.23

LYZ1

C1

-14.76

 

FOLR11

C1

-3.21

FN11

C1

-12.26

 

CST31

C8

-2.80

CSF1R

C8

-8.15

 

SLA-DQB1

C8

-2.74

TGFBI

C8

-6.78

 

SLA-DOB

C8

-2.69

CST31

C8

-6.51

 

CST21

C8

-2.67

CST21

C8

-5.80

 

SLA-DRA

C8

-2.65

CD163

No3

-5.59

 

SLA-DQA1

C8

-2.40

CTSZ

C8

-5.58

  1. 1 Genes that are commonly down-regulated after LPS or PMA/ionomycin stimulation
  2. 2 The clusters refer to the hierarchical clustering reported in Figure 2 and Additional file 4
  3. 3 "No" means that the genes were found differentially expressed in only one stimulation condition and were not included in the hierarchical clustering.
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BMC Genomics

ISSN: 1471-2164

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