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Table 1 Characteristics of skin and mucosal wounds [1, 2, 7, 9]

From: Positional differences in the wound transcriptome of skin and oral mucosa

 

Skin

Tongue

Re-epithelialization at 24 h

40%

100%

Inflammatory infiltrates

  

   MPO (U/mg protein) at 24 h

2.82 ± 0.2

1.26 ± 0.2

   Mϕ (HPF) at 72h

10.8 ± 0.3

6.7 ± 0.4

   T cells (HPF) at day 7

15.1 ± 1.5

5.6 ± 0.3

Cytokine/chemokine

  

   IL-6

↑↑

↑

   IL-a

↑↑

↑

   IL-1β

↑↑

↑

   TNF-α

↑↑

↑

   TGF-β1

↑↑

↑

   TGF-β3

↑

↑↑

   KC

↑↑

↑

Angiogenesis

  

   Vessel density compared to normal tissue at day 5 (fold increase)

11.5

3.4

   VEGF

↑↑

No marked change

Collagen fibril diameter in wound

Decreased

No marked change