Figure 5

A circular overview of five Giardia P15 contigs. A circular overview of the five largest contigs in the P15 assembly which in total represent 909 kb of the genome (about 8%). The most outer graph displays G + C content plotted in overlapping 1.5 kb windows along the contigs. Areas where the G + C content is elevated (>50%) is displayed in red. The middle graph displays atypical nucleotide composition (as defined in Methods), plotted in overlapping 1.5 kb windows. Radial lines represent genes, with different colors for different annotations (blue = Hypothetical protein, red = Variant-specific surface protein (VSP), Reverse transcriptase (RT) or High cysteine membrane protein (HCMP), yellow = NEK Kinase, purple = Protein 21.1, green = other). The most inner graph displays the level of sequence coverage. VSP, RT and HCMP genes are characterized by a higher than average G+C content and atypical nucleotide signatures. These genes are dispersed and create chromosomal islands with higher than average G + C.