Skip to main content

Table 4 Inconsistencies between information from NCBI protein database and SHV mutation table

From: SHV Lactamase Engineering Database: a reconciliation tool for SHV β-lactamases in public databases

GI

Name and mutation profile according to

Inconsistency

 

NCBI protein database

SHV mutation table*

 

262044380

SHV-5 [G238S E240K]

SHV-like [P252L]

different mutation profile

41584432

SHV-5 [G238S E240K]

SHV-like [T235N G238S E240K]

 

51105097

SHV-5 [G238S E240K]

SHV-like [R6L G238S E240K]

 

40950644

SHV-5 [G238S E240K]

SHV-12 [L35Q G238S E240K]

 

41584438

SHV-5 [G238S E240K]

SHV-like [L35Q T235N G238S E240K]

 

41584428

SHV-5 [G238S E240K]

SHV-like [L35Q T235N G238S E240K S271N]

 

41584434

SHV-5 [G238S E240K]

fragment (C-1) of SHV-12 [L35Q G238S E240K]

a fragment with different mutation profile

41584430

SHV-5 [G238S E240K]

fragment (C-1) of SHV-like [L35Q T235N G238S E240K]

 

40950646

SHV-5 [G238S E240K]

fragment (C-2) of SHV-like [L35Q D233E G238S E240K]

 

157838542

SHV-7 [I8F R43S G238S E240K]

fragment (N-19 C-2) of SHV-like [R43S G238S E240K]

 

77702548

SHV-11 [L35Q]

SHV-1 (no mutation)

different mutation profile

90403947

SHV-12 [L35Q G238S E240K]

fragment (C-4) of SHV-like [L35Q G238S E240K E288F]

a fragment with different mutation profile

90403949

SHV-12 [L35Q G238S E240K]

fragment (N-2 C-7) of SHV-like [Y7W I8V R9I L10F C11P L35Q G238S E240K]

 

90403945

SHV-12 [L35Q G238S E240K]

fragment (N-9 C-1) of SHV-like [L35Q G238S E240K E288N H289L W290G Q291T]

 

90403951

SHV-12 [L35Q G238S E240K]

fragment (N-10 C+1) of SHV-like [L35Q G238S E240K A284R A285P L286Y I287K E288N H289L W290E Q291P R292K]

 

15718691

SHV-16 [-162.1D -162.2R -162.3W -162.4E -162.5T]

SHV like [H96T Y97H -162.1D -162.2R -162.3W -162.4E -162.5T]

different mutation profile

255045865

SHV-28 [Y7F]

fragment (N-6 C-20) of SHV-1

a fragment with different mutation profile

30230495

SHV-48 [V119I]

SHV-like [L35Q R191H G238S E240K]

different mutation profile

33943602

SHV-56 [L35Q K234R]

SHV-like [S14Y L35Q G238S E240K]

 

83596180

SHV-71[H112Y A146V]

SHV-like [L35Q G238S E240K N254D]

 

84380855

SHV-86 [L35Q G238S E240R]

SHV-like [Y7F L35Q G238S E240R]

 

159138975

SHV-102 [G238A]

fragment (N-24 C-5) of SHV-like [L35Q E168A G251S]

a fragment with different mutation profile

159138973

SHV-102 [G238A]

fragment (N-23 C-5) of SHV-like [L35Q E168A G251S]

 

154269503

SHV-103 [L250R]

SHV-like [K256R]

different mutation profile

161367444

SHV-104 [M5L R202S]

SHV-like [R202S]

 

257359515

SHV-121 [I8A A22V L35Q M129V]

SHV-like [T18A A22V L35Q M129V]

 

256862196

SHV-123 [L35Q G238S E240K P252G N254I]

fragment (C-15) of SHV-like [L35Q G238S E240K P252G N255I]

a fragment with different mutation profile

  1. * SHV-like: SHV variant with a mutation profile that is not in the SHV mutation table