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Table 3 Composition of 'normal' and 'disease' panels

From: Evaluation of external RNA controls for the standardisation of gene expression biomarker measurements

RNA standards

Copies/ng total RNA

Fold change (B/A)

 

Panel A

Panel B

 

13

1 × 105

1 × 105

1.0

42

1 × 104

5 × 103

0.5

81

1 × 102

1 × 102

1.0

84

1 × 102

5 × 102

5.0

95

1 × 103

1 × 103

1.0

99

8 × 103

1.2 × 104

1.5

113

1 × 101

1 × 101

1.0

171

1 × 101

1 × 102

10.0

  1. To mimic the composition of 'normal' and 'disease' states which contain both differentially expressed genes (DEGs) and non-DEGs, two panels were produced using the eight standards at defined ratios and copy numbers.
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BMC Genomics

ISSN: 1471-2164

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