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Table 5 Top 10 candidate genes for SCA22 by using PIN

From: Prioritizing disease candidate genes by a gene interconnectedness-based approach

Rank ICN RW PR ICN-RW ICN-PR RW-PR ICN-RW-PR
1 SPTA1 NRAS YY1AP1 SPTA1 SPTA1 SPTA1 SPTA1
2 GNAT2 SPTA1 ECM1 GNAT2 YY1AP1 AHCYL1 GNAT2
3 TAF13 GNAT2 AHCYL1 NRAS GNAT2 NRAS NRAS
4 ISG20L2 GNAI3 FDPS ISG20L2 TAF13 ECM1 YY1AP1
5 FCGR2C AHCY1 SPTA1 FCGR2C ECM1 YY1AP1 ECM1
6 YY1AP1 STXBP3 STXBP3 TAF13 NRAS GNAT2 TAF13
7 PSMD4 ECM1 S100A7 PSMD4 STXBP3 STXBP3 STXBP3
8 NRAS CCT3 POLR3C GNAI3 PSMD4 GNAI3 AHCYL1
9 NGF RPS27 UBAP2L NGF POLR3C S100A7 GNAI3
10 NTRK1 S100A7 GNAT2 NTRK1 NGF FDPS PSMD4