Table 5 Top 10 candidate genes for SCA22 by using PIN
From: Prioritizing disease candidate genes by a gene interconnectedness-based approach
Rank | ICN | RW | PR | ICN-RW | ICN-PR | RW-PR | ICN-RW-PR |
|---|---|---|---|---|---|---|---|
1 | SPTA1 | NRAS | YY1AP1 | SPTA1 | SPTA1 | SPTA1 | SPTA1 |
2 | GNAT2 | SPTA1 | ECM1 | GNAT2 | YY1AP1 | AHCYL1 | GNAT2 |
3 | TAF13 | GNAT2 | AHCYL1 | NRAS | GNAT2 | NRAS | NRAS |
4 | ISG20L2 | GNAI3 | FDPS | ISG20L2 | TAF13 | ECM1 | YY1AP1 |
5 | FCGR2C | AHCY1 | SPTA1 | FCGR2C | ECM1 | YY1AP1 | ECM1 |
6 | YY1AP1 | STXBP3 | STXBP3 | TAF13 | NRAS | GNAT2 | TAF13 |
7 | PSMD4 | ECM1 | S100A7 | PSMD4 | STXBP3 | STXBP3 | STXBP3 |
8 | NRAS | CCT3 | POLR3C | GNAI3 | PSMD4 | GNAI3 | AHCYL1 |
9 | NGF | RPS27 | UBAP2L | NGF | POLR3C | S100A7 | GNAI3 |
10 | NTRK1 | S100A7 | GNAT2 | NTRK1 | NGF | FDPS | PSMD4 |