From: Maximizing biomarker discovery by minimizing gene signatures
Gene | General description | Support | Endpoint D | Endpoint E | ||
---|---|---|---|---|---|---|
 |  |  | Overlap | Position | Overlap | Position |
CA12 | Highly correlated with Erα | + | 67 | -5 | 61 | 4 |
MAPT | prognostic values in ER(+) Primary breast cancers in 3 patient cohorts | + | 43 | -7 | 22 | 26 |
ESR1 | Involved in pathological processes of breast cancer | + | 33 | -2 | 53 | 1 |
GATA3 | A breast cancer marker | + | 25 | -14 | 40 | 6 |
BTG3 | Protein coding | Â | 22 | 75 | Â | -142 |
NFIB | Differentially expressed reported [39] | Â | 22 | 84 | 20 | -61 |
LDHB | Protein coding | Â | 21 | 27 | Â | -239 |
RARRES1 | Downregulated reported [40] | Â | 20 | 2 | 19 | -2 |
CCND1 | Aberrantly regulated and could contribute to therapeutic failure in the context of ER-positive breast cancer | + | 18 | -56 | Â | 145 |
ELF5 | Downregulated reported [41] | Â | 16 | 7 | Â | -16 |
IL6ST | Protein coding | Â | Â | -60 | 33 | 60 |
SLC39A6 | Coregulated with estrogen receptor in some breast cancers | + | Â | -64 | 25 | 41 |
TBC1D9 | Protein coding | Â | Â | -25 | 25 | 19 |
ABAT | Protein coding | Â | Â | -34 | 16 | 29 |