Groupa | Normal (n = 103)b | Carrier (n = 37) | Affected (n = 35)c |
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Pre-challenge | 482.42 ± 41.30 | 573.93 ± 89.14 | 1635.27 ± 148.22 |
Post-challenge | 644.37 ± 68.80 | 469.26 ± 51.08 | 1928.46 ± 136.37 |
- a Pre-challenge was at 7 weeks of age, post-challenge was at 8 weeks of age after isoflurane treatment.
- b Mean and standard error of plasma CPK in units/liter. Of 192 pigs that were sampled, not all the normal animals were challenged with isoflurane anesthesia.
- c Values were not different before or after challenge; affected pigs had significantly greater CPK activity than normal or carrier pigs (p < 0.0001).