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Table 2 Results of the Gene Ontology (GO) analysis including closest genes to SNP with P<5.0E-05

From: A genome wide association study for backfat thickness in Italian Large White pigs highlights new regions affecting fat deposition including neuronal genes

Go sub-ontology GO term accession GO term description Number of involved genes Involved genes DAVID P-value
Biological Process GO:0050767 regulation of neurogenesis 5 ACTR3, LINGO1, IRX3, XRCC2, DLL1 0.015
Biological Process GO:0006928 cell motion 8 ACTR3, CXCR4, SPOCK1, SCNN1G, IL12B, APBB2, ELMO1, CTNNA2 0.018
Biological Process GO:0051960 regulation of nervous system development 5 ACTR3, LINGO1, IRX3, XRCC2, DLL1 0.024
Biological Process GO:0060284 regulation of cell development 5 ACTR3, LINGO1, IRX3, XRCC2, DLL1 0.029
Biological Process GO:0030182 neuron differentiation 7 LINGO1, CXCR4, MTPN, APBB2, OLFM3, NTM, CTNNA2 0.038
Biological Process GO:0045664 regulation of neuron differentiation 4 ACTR3, LINGO1, IRX3, DLL1 0.040
Biological Process GO:0048666 neuron development 6 LINGO1, CXCR4, APBB2, OLFM3, NTM, CTNNA2 0.044
Molecular Function GO:0031420 alkali metal ion binding 5 KCNK9, KCNT2, ATP1B3, SLC22A4, SCNN1G 0.031
Molecular Function GO:0000166 nucleotide binding 19 RBM24, XRCC2, SUCLG2, PKN2, ABCB1, ACTR3, MAP3K5, KCNT2, HIPK1, ASCC3, PDE1C, CELF4, SLC22A4, CELF2, DPYD, RAB38, DOCK10, ARL4C, MOCS1 0.038
Cellular Component GO:0043005 neuron projection 7 NUMA1, CXCR4, MTPN, PARK2, APBB2, DTNBP1, CTNNA2 0.009
Cellular Component GO:0031252 cell leading edge 4 ACTR3, CXCR4, APBB2, CTNNA2 0.037