Figure 12
Self organizing tree algorithm (SOTA) clusters of transcription factor transcript levels in response to hypoxia. Eleven clusters were identified in MeV using the SOTA function. Grey lines are the individual transcription factor transcript level, and pink is the average trend line for a given cluster. The majority of transcripts are not associated with a pathway, and therefore no significant categories, other than DNA binding, were detected among the clusters. Each tick mark on the X-axis represents each time point in the experiment, and each tick mark on the Y-axis represents a fold change in transcript level. The box marked with an asterisk represents the cluster containing the known hypoxia responsive transcription factor, SrbA. These transcripts are further evaluated in Figure 13.