A study on promoter characteristics of head-to-head genes in Saccharomyces cerevisiae

BMC Genomics

Table 3 TFs that prefer regulation of h2h genes

TF	#h2h¹	e-score²	f-score³	#PPI⁴	%PPI⁵	#gene⁶	%h2h⁷
STP2	7	0.375	4.358	3	42.9	235	6.0
RME1	6	0.240	3.437	0	0.0	156	7.7
PDR3	12	0.288	2.931	2	16.7	446	5.4
SFP1	22	0.335	2.452	0	0.0	432	10.2
GCN4	195	0.269	2.250	1	0.5	2,058	19.0
SFP1	42	0.335	2.225	0	0.0	886	9.5
RPN4	41	0.248	2.130	0	0.0	169	48.5
FHL1	57	0.273	2.101	0	0.0	1,120	10.2
MET4	757	0.330	2.034	26	3.4	19,090	7.9

¹ Number of h2h gene pairs both bound/regulated by the TF. ² Average co-expression of the h2h gene pairs. ³ Average functional similarity of the h2h gene pairs. ⁴ Number of the h2h gene pairs with interactions. ⁵ Ratio of the h2h gene pairs with interactions. ⁶ Number of genes bound/regulated by the TF with evidence. ⁷ Ratio of genes bound/regulated by the TF that are h2h genes.

ISSN: 1471-2164