Table 3 Common functional classes unifying genes up- and downregulated during myogenic differentiation

1

Protein modification/assembly

ubiquitination/proteolysis

305

UP

16,07

4,118E-23

7,67E-20

10_up

162

DOWN

39,51

2,97E-05

0,055652

19_down

protein complex assembly

131

UP

9,16

0,0001135

0,21125

11_up

177

DOWN

30,51

7,01E-17

2,11E-13

20_down

2

Transport/localization

transport/localization

243

UP

16,05

1,299E-17

2,42E-14

12_up

279

DOWN

41,22

1,27E-11

2,39E-08

21_down

3

Transcription

transcription regulation

458

UP

13,32

7,64E-10

1,42E-06

13_up

36

DOWN

41,67

0,000311

0,57965

22_down

transcription (-) reg,

148

UP

11,49

9,994E-07

0,001862

14_up

203

DOWN

36,45

1,19E-09

2,23E-06

23_down

chromatin organization/modification

86

UP

9,30

0,0005777

1,070598

15_up

153

DOWN

30,72

5,88E-23

1,1E-19

24_down

4

Apoptosis

apoptosis

216

UP

17,59

8,615E-07

0,001605

16_up

216

DOWN

38,43

1,26E-08

2,36E-05

25_down

5

Signaling

reg, of kinase activity

204

UP

15,69

1,362E-06

0,002537

17_up

233

DOWN

40,77

2,22E-06

0,00416

26_down

6

Cell morphogenesis

cytoskeleton organization

130

UP

14,62

0,0002361

0,438978

18, 19_up

193

DOWN

35,23

1,05E-17

1,96E-14

27_down