Table 1 Similarity between XaPPTase and other PPTases involved in NRPS and fatty acid biosynthesis in bacteria (from[25])
Pathways | Proteins | Organisms a | Experimentally-determined specificities (A/P)b | Domain I | Spacing between domains I and II (in aa) | Domain II | Overall amino acid identities / similarities with XabA |
|---|---|---|---|---|---|---|---|
Albicidin and unknown | XabA | X. albilineans str. LS155 | Pc | GVGID LERP | --(x)39-- | FS AKES LFK AAY | - |
AlbXXI | X. albilineans str. Xa23R1 | ? | GVGID LERP | --(x)39-- | FS AKES LFK AAY | 100% /- | |
XaPPTase | X. albilineans str. GPE PC73 | ? | GVGID LERP | --(x)39-- | FS AKES LFK AAY | 94% / 95% | |
XaPPTase | Xanthomonas spp. str. XaS3 | ? | GVGID LERM | --(x)39-- | FS AKES LFK AAY | 83% / 87% | |
Unknown | XaPPTase | All sequenced X. oryzae strains* | ? | GIGID LEHL | --(x)38-- | FS AKES LFK ASF | 40% / 51% |
Unknown | XaPPTase | X. sacchari str. NCPPB4393 | ? | GIG LD VERV | --(x)38-- | FS AKES FYK AAA | 41% / 55% |
Unknown | BBta_3710 | Bradyrhizobium spp. BTAi | ? | ALG LD IEDV | --(x)35-- | FS AKEA YYK CQY | 25% / 36% |
Enterobactin | EntD | E. coli str. K12 substr. MG1655 | Pd | PIGID IEEI | --(x)36-- | FS AKES AFK ASE | 23% / 31% |
Mycobactin | PptT | M. tuberculosis str. CSU93 | Pe | SVGID AEPH | --(x)35-- | FC AKEA TYK AWF | 25% / 34% |
Gramicidin | Gsp | Bacillus brevis str. ATCC 9999 | Pd | PVGID IERI | --(x)35-- | WT IKES YIK AIG | 14% / 21% |
Surfactin | Sfp | Bacillus subtilis str. RB14 | A/Pf | PIGID IEKT | --(x)35-- | WS MKES FIK QEG | 17% / 25% |
Fatty acids | AcpS | E. coli str. K12 substr. MG1655 | Ad | GLG TD IVEI | --(x)40-- | F AVKEA AAK AFG | 9% / 14% |
Fatty acids | AcpT | E. coli str. K12 substr. MG1655 | ? | EVG CD IEVI | --(x)34-- | WT RKEA IVK QRG | 13% / 22% |
Fatty acids | AcpS | M. tuberculosis str. CSU93 | Ae | GVGID LVSI | --(x)41-- | W AAKEA VIK AWS | 11% / 17% |
Unknown | HetI | X. albilineans str. GPE PC73 | ? | RLGVD IERQ | --(x)37-- | WC AKEA LLK AHG | 25% / 31% |
Unknown | HetI | Xanthomonas spp. str. XaS3 | ? | RLGVD IERQ | --(x)37-- | WC AKEA LLK AHG | 22% / 28% |
Unknown | HetI | All sequenced X. oryzae strains | ? | RLGVD LERI | --(x)37 -- | WC AKEA LLK AYG | 20% / 25% |
Consensus | (V/I)G(I/V)D** | (F/W)(S/C/TxKE(S/A)xxK** |