Figure 3
From: Intronic Non-CG DNA hydroxymethylation and alternative mRNA splicing in honey bees
CHH modifications are primarily in the introns of genes coding for transcription factors. a, EHB and AHB intron methylation at CHH sites is enriched in the GO category “regulation of transcription” at the indicated FDR P values. There are 858 genes with >10% CHH modifications in EHB and 529 genes with >5% CHH modifications in AHB. Analysis with DAVID[32]. b, Distalless is a Hox gene and a transcription factor with high amounts of CHH modifications in the introns of both AHB and EHB.