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Figure 6 | BMC Genomics

Figure 6

From: Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatin

Figure 6

Human genomic DNA with one CG encompassing POLR1B gene. Horizontal green bar marks the CGI position. Track labeled “Short Match” marks the position of CpGs. Track-labeled “MLL1 sites” marks morpheme positions; “non-motifs” mark the position of sequences not found in results of SELEX assays [24]. Track labeled “Layered H3K4me3” shows the position of H3K4me3 marks, determined by the ENCODE project using a variety of cell lines including: lymphoblastoid cells (GM12878), H1 human embryonic stem cell line (H1-hESC), human skeletal muscle myoblasts (HSMM), human umbilical vein endothelial cells (HUVEC), erythroleukemia type cell line (K562), normal human epidermal keratinocytes (NHEK), and normal human lung fibroblasts (NHLF) [59]. A layered representation is displayed in order to provide an overview of H3K4me3 profiles [59].

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