Figure 6From: Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatinHuman genomic DNA with one CG encompassing POLR1B gene. Horizontal green bar marks the CGI position. Track labeled “Short Match” marks the position of CpGs. Track-labeled “MLL1 sites” marks morpheme positions; “non-motifs” mark the position of sequences not found in results of SELEX assays [24]. Track labeled “Layered H3K4me3” shows the position of H3K4me3 marks, determined by the ENCODE project using a variety of cell lines including: lymphoblastoid cells (GM12878), H1 human embryonic stem cell line (H1-hESC), human skeletal muscle myoblasts (HSMM), human umbilical vein endothelial cells (HUVEC), erythroleukemia type cell line (K562), normal human epidermal keratinocytes (NHEK), and normal human lung fibroblasts (NHLF) [59]. A layered representation is displayed in order to provide an overview of H3K4me3 profiles [59].Back to article page