Figure 3

Network of GTF2E1 interacting proteins. Network of interacting proteins with up to second-degree connection to GTF2E1 based on data from the reactome dataset [28]. Of note, GTF2E1 has a direct interaction with ERCC2 (XPD). Below the Figure is a graphical summary interpretation depicting the three cellular pathways representing the majority of protein networks with first or second-degree connection to ERCC2 (i.e., Transcription, Cell Cycle, DNA Repair). The GTF2E1-ERCC2 connection highlights the transcription process (depicted in the left side of the figure).