Table 5 Top 20 hub genes and number of connections induced by infection of human monocyte-derived macrophages with M. avium isolates
Mah 1655 | Mah V101 | Maa 1794 | |||
|---|---|---|---|---|---|
Gene ID | No. of interactions | Gene ID | No. of interactions | Gene ID | No. of interactions |
TNF | 61 | TNF | 178 | TNF | 219 |
IL1B | 43 | IL6 | 117 | IL6 | 141 |
IL6 | 38 | IL1B | 113 | IL1B | 127 |
NFKBIA | 34 | NFKBIA | 81 | NFKBIA | 93 |
NFKB1 | 27 | IL10 | 80 | FOS | 88 |
IL1A | 22 | NFKB1 | 70 | NFKB1 | 76 |
PTGS2 | 19 | FOS | 69 | CSF2 | 66 |
NFKB2 | 18 | CSF2 | 59 | ILIA | 63 |
CXCL2 | 18 | ILIA | 58 | BCL2 | 59 |
CCL5 | 18 | JUN | 57 | OSM | 59 |
OSM | 17 | CD40 | 53 | CD40 | 58 |
TNFAIP3 | 14 | PTGS2 | 52 | PTGS2 | 56 |
CCL3L1 | 14 | Rb1 | 50 | SRC | 55 |
LIF | 14 | BCL2 | 47 | RB1 | 50 |
CCL20 | 14 | OSM | 47 | IL15 | 50 |
REL | 13 | VEGFA | 46 | CXCL2 | 45 |
SOD2 | 13 | SRC | 43 | CCL5 | 42 |
NFKBIB | 11 | CCL5 | 42 | PIK3R1 | 42 |
CCL3 | 11 | CXCL2 | 42 | CEBPA | 41 |
TRAF1 | 10 | NFKB2 | 38 | TICAM1 | 41 |