Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria

Table 3 Detected putative lanthipeptide gene clusters

	Phylum	Lanthipeptide class	Locus tag of the lanthipeptide modifying enzyme Lan	Similar to^†	Reference^#
Clostridium cellulovorans 743B, ATCC 35296	Firmicutes	I	Clocel_4251
			Clocel_4256
			Clocel_4262
Clostridium kluyveri DSM 555	Firmicutes	I	CKL_3505
Bifidobacterium longum DJO10A	Actino-bacteria	II	BLD_1651		[25]
Clostridium acetobutylicum ATCC 824	Fimicutes	II	CA_C0082
Clostridium acetobutylicum DSM 1731	Fimicutes	II	SMB_G0083
Clostridium acetobutylicum EA 2018	Fimicutes	II	CEA_G0073
Clostridium beijerinckii NCIMB 8052	Fimicutes	II	Cbei_4586		[25]
Clostridium botulinum H04402 065	Fimicutes	II	H04402_00616 H04402_00617	lichenicidin
Clostridium cellulovorans 743B, ATCC 35296	Fimicutes	II	Clocel_0875	lichenicidin	[32]
		II	Clocel_ 4225
			Clocel_4228
Caldicellulosiruptor lactoaceticus 6A, DSM 9545	Fimicutes	II	Calla_2060
Caldicellulosiruptor bescii Z-1320, DSM 6725	Fimicutes	II	Athe_1107	lichenicidin	[32]
Caldicellulosiruptor kristjanssonii 177R1B, DSM 12137	Fimicutes	II	Calkr_0299
Bifidobacterium longum infantis JCM 1222, ATCC 15697	Actino-bacteria	IV	BLIJ_0470
Propionibacterium acnes TypeIA2 P.acn17	Actino-bacteria	IV	TIA2EST22_11370

^†Cluster shows similarities to characterized RiPP cluster; ^#Cluster was previously detected by genome mining approaches.

ISSN: 1471-2164