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Table 8 Mean and standard deviation of the Pearson correlation for the SVR models constructed from subsets of SNPs selected by adjusted p-values of the simulated database 2.

From: SNPs selection using support vector regression and genetic algorithms in GWAS

Group SNP selection with adjusted p-values # SNPs Linear** RBF** PUK**
1 < 10-9 1a 0.53(0.07) 0.94(0.04) 0.95(0.04)
2 < 10-8 1a 0.53(0.07) 0.94(0.04) 0.95(0.04)
3 < 10-7 1a 0.53(0.07) 0.94(0.04) 0.95(0.04)
4 < 10-6 1a 0.53(0.07) 0.94(0.04) 0.95(0.04)
5 < 10-5 1a 0.53(0.07) 0.94(0.04) 0.95(0.04)
6 < 10-4 1a 0.53(0.07) 0.94(0.04) 0.95(0.04)
7 < 10-3 1a 0.53(0.07) 0.94(0.04) 0.95(0.04)
8 < 10-2 1a 0.53(0.07) 0.94(0.04) 0.95(0.04)
9 < 10-1 3b 0.53(0.07) 0.94(0.04) 0.95(0.04)
10 < 0.20 4c 0.53(0.07) 0.94(0.04) 0.95(0.04)
11 < 0.30 4c 0.53(0.07) 0.94(0.04) 0.95(0.04)
12 < 0.40 4c 0.53(0.07) 0.94(0.04) 0.95(0.04)
13 < 0.50 4c 0.53(0.07) 0.94(0.04) 0.95(0.04)
14 < 0.60 4c 0.53(0.07) 0.94(0.04) 0.95(0.04)
15 < 0.70 4c 0.53(0.07) 0.94(0.04) 0.95(0.04)
16 < 0.80 4c 0.53(0.07) 0.94(0.04) 0.95(0.04)
17 < 0.90 4c 0.53(0.07) 0.94(0.04) 0.95(0.04)
  1. *Adjusted p-values of the Spearman correlation with Bonferroni correction.
  2. ** Mean and standard deviation of the Pearson correlation in 10-fold cross validation.
  3. (a) Only the SNP3. (b) Only SNPs 3, 4 and 5. (c) Only SNPs 3, 4, 5 and 8964.
  4. For each group defined after the first selection, a model SVR was constructed, evaluated for each kernel, through the Pearson correlation coefficient in 10-fold cross validation. The bold line indicates the best model from the first selection for PUK.