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Table 2 Target genes with highest RankSpec values for different anatomical structures of the brain.

From: Prediction of tissue-specific effects of gene knockout on apoptosis in different anatomical structures of human brain

Structure

Rank

1

2

3

4

5

6

7

8

9

10

cerebellum

NR3C1*

PAN2

CYTSA

DPYSL2

GABRB3*

GABRG2

NPM1*

ABL2*

ACAT2

PITPNA

pons

FOXA2

ESR1*

PPARG*

NR1D2

ESRRG

NTN1*

UNC5B*

THRA*

NR4A2*

FOXO1*

thalamus

DPYSL2

FOXA2

FOXO1*

PITPNA

CRMP1

PTGDS

RORA

CDK5*

DPYSL4

MCAT

hypothalamus

FOXA2

FOXO1*

NFATC1

POMC

NR2F2

NKX2-2

TBXA2R

TACR2

FZD10

NTS

basal ganglia

FOXO1*

FOXA2

TPM1

SYN1

GAD2

MCM7

LRP6*

ACTN2*

MCM3

SST*

amygdala

MYB

NPY1R

NR2F2

NPY

PNOC

PDYN

ZNF32

ATF1

RGS7

FOXO1*

hippocampus

DPYSL2

CRMP1

PRKCA*

CDK5*

PA2G4*

DCC*

NOP58

DPYSL4

ERBB2

WNT3A*

cingulate gyrus

SQSTM1*

AES*

NEDD4L

PITPNA

ADCY2

SHC2

BTRC

NTRK2*

ZFPM1

MEF2C*

temporal lobe

AES*

ADCY2

SQSTM1*

NEDD4L

KIDINS220

STAT6

SHC2

NTRK2*

MEF2C*

CCK*

parietal lobe

AES*

STAT6

SQSTM1*

ADCY2

KIDINS220

NEDD4L

MEF2C*

RPF1

ZFPM1

CCK*

frontal lobe

SQSTM1*

AES*

NEDD4L

ADCY2

SHC2

BTRC

STAT6

MEF2C*

TRAF3*

ECSIT

occipital lobe

AES*

ERBB4*

UBE2D2

MEF2C*

ADRBK1

RPF1

DNM1

PTTG1

PRKCB*

KIDINS220

  1. * target genes involved in "apoptotic process" GO category