Figure 3

Transcriptome gene expression analysis. a - hierarchical cluster dendrogram based on the expression levels of 100 genes with a highest variance between samples; b - principal component analysis of expression based on the same set of genes as in a. The horizontal axis represents the first principal component of variation - a projection of the array data representing the maximal variance among them (80% of total variance between samples). The vertical axis represents the second principal component of variation (13% of total variance); c - example of heat-map presentation of gene expression profiles of correctly reprogrammed genes in mink EF, ES and iPS cells. Each row of the heat-map corresponds to one gene, and expression levels are shown using color-code (blue color represents the lowest expression level, red color - the highest); d - example of heat-map presentation of gene expression profiles of not reprogrammed genes in mink EF, ES and iPS cells.