Figure 7From: Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancerQuantitative mass spectrometry based proteomic analysis after EZH2 inhibition. A) Protein expression differences of selected cell cycle regulators in EPZ-6438 (Epizyme®, Cambridge, MA) versus DMSO treated lymphoma cells (WSU-DLCL2) are represented as log2 ratios. B) Global protein expression changes after 8 days of EPZ-6438 treatment. Down-regulated cell cycle regulators are highlighted in dark blue.Back to article page