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Table 3 Genes induced in PE

From: Hypoxia-activated genes from early placenta are elevated in Preeclampsia, but not in Intra-Uterine Growth Retardation

Gene symbol

Gene name

Maximal signal

Protein category

Chromosomal localization

Library address

16S ribosomal RNA

16S ribosomal RNA

one PE case

Transcription/Translation

Mitochondrie

18B8

16S ribosomal RNA

16S ribosomal RNA

PE+IUGR

Mitochondrial metabolism

Mitochondrie

14H2

18S rRNA

ARN 18S

severe PE

Transcription/Translation

 

13F12

ACTG1

actin, gamma 1

several PE

Structure protein

17q25

22G1

angiopoietin-like 4

ANGPTL4 = PPARG angiopoietin related protein

several PE

Transcription/Translation

19p13.3

11D9

ATP5B

ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide

several PE

Mitochondrial metabolism

12p13-qter

11A4

ATP6

ATP synthase F0 subunit 6

several PE

Mitochondrial metabolism

Mitochondrie

16D7

C9orf90

chromosome 9 open reading frame 90 DKFZp762G199

one PE case

 

9q34.13

2C10

CDC37

CDC37 cell division cycle 37 homolog (S. cerevisiae)

several PE

Cell cycle

19p13.2

10E10

CGA

glycoprotein hormones, alpha polypeptide

several PE

Signal transduction

6q12-21

23B10

CGA

glycoprotein hormones, alpha polypeptide

several PE

Signal transduction

6q12-21

2C5

CGA

glycoprotein hormones, alpha polypeptide

several PE

Signal transduction

6q12-21

23D12

CGA

glycoprotein hormones, alpha polypeptide

several PE

Signal transduction

6q12-21

10H5

CGA

glycoprotein hormones, alpha polypeptide

several PE

Signal transduction

6q12-21

2H4

CGA

glycoprotein hormones, alpha polypeptide

several PE

Signal transduction

6q12-21

16D5

CGA

glycoprotein hormones, alpha polypeptide

Terms/PE

Signal transduction

6q12-21

8B8

COX1

Cytochrome c oxidase subunit I

several PE

Mitochondrial metabolism

Mitochondrie

13H7

COX1

Cytochrome c oxidase subunit I

several PE

Mitochondrial metabolism

Mitochondrie

15B3

COX1

Cytochrome c oxidase subunit I

several PE

Mitochondrial metabolism

Mitochondrie

12H9

COX1

Cytochrome c oxidase subunit I

several PE

Mitochondrial metabolism

Mitochondrie

18D6

COX2

Cytochrome c oxidase subunit II

one PE case

Mitochondrial metabolism

Mitochondrie

8B7

COX3

Cytochrome c oxidase subunit III

several PE

Mitochondrial metabolism

Mitochondrie

20F4

CSHL1

chorionic somatomammotropin hormone-like 1

several PE

Signal transduction

17q24.2

19A7

CSNK1A1

Casein kinase 1, alpha 1

one PE case

Signal transduction

5q32

18A8

DDX3X

DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked

one PE case

Transcription/Translation/Modifi

p11.3-11.23

17F11

DKFZP434F2021

DKFZP434F2021 protein

one PE case

 

3q13.2

6A3

DKFZp586F1223

Hs.28540

severe PE

 

11q23

20F7

EEF1A1

eukaryotic translation elongation factor 1 alpha 1

one PE case

Transcription/Translation

6q14.1

7A11

EIF4B

eukaryotic translation initiation factor 4B

one PE case

Transcription/Translation

12q13.13

2C7

ERVWE1

endogenous retroviral family W, env(C7), member 1 (syncytin)

one PE case

Cell-cell contacts

7q21-22

8G1

FEM1C

fem-1 homolog c (C.elegans)

PE+IUGR

Transcription/Translation

5q22

16D6

FEM1C

fem-1 homolog c (C.elegans)

PE+IUGR

Transcription/Translation

5q22

8D9

FLJ11149

riboflavin kinase

one PE case

Transport

9q21.31

23F12

FLJ22728

hypothetical protein FLJ22728 DKFZp761I1913

several PE

Transport

11p15.2

23G6

FLJ22728

hypothetical protein FLJ22728 DKFZp761I1913

several PE

Transport

11p15.2

23B6

GAPD

glyceraldehyde-3-phosphate dehydrogenase

several PE

Mitochondrial metabolism

12p13

23D3

GAPD

glyceraldehyde-3-phosphate dehydrogenase

several PE

Mitochondrial metabolism

12p13

24B3

GLIPR1

GLI pathogenesis-related 1 (glioma)

PE+IUGR

 

12q21.1

16G10

H19

H19, imprinted maternally expressed untranslated mRNA

several PE

RNA gene

11p15.5

18C1

H3F3B

H3 histone, family 3B (H3.3B)

severe PE

Chromatin structure

17q25

11C8

IL8

interleukin 8

severe PE

Apoptose regulation

4q13-q21

12G11

ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

one PE case

Cell-cell contacts

2q31-32

11B11

LAMA5

laminin, alpha 5

one PE case

Apoptose regulation

20q13.2-13.3

1C3

LOC126731

LOC126731

Terms/PE

 

1q42.13

24F2

LOC374933

Homo sapiens LOC374933 (LOC374933),

PE+IUGR

 

1p36.33

21G10

MAN1

integral inner nuclear membrane protein

one PE case

Transcription/Translation/Modifi

12q14

7A7

MATR3

Matrin 3

severe PE

Transcription/Translation/Modifi

5q31.3

3C8

MGC2714

hypothetical protein MGC2714

PE+IUGR

 

11q22.2

13C7

ND1

NADH dehydrogenase subunit 1

several PE

Mitochondrial metabolism

Mitochondrie

12C4

ND3

NADH dehydrogenase subunit 3

several PE

Mitochondrial metabolism

Mitochondrie

18H7

NRCAM

neuronal cell adhesion molecule

one PE case

Cell-cell contacts

7q31.1-q31.2

18F11

NUFIP1

nuclear fragile × mental retardation protein interacting protein 1

several PE

RNA-interacting factor

13q14

4E6

OSBPL2

oxysterol binding protein-like 2

one PE case

Signal transduction

20q13.3

1C3

PSG4

pregnancy specific beta-1-glycoprotein 4

one PE case

Signal transduction

19q13.2

16C9

PSG4

pregnancy specific beta-1-glycoprotein 4

one PE case

Signal transduction

19q13.2

11A9

PSG5

pregnancy specific beta-1-glycoprotein 5

several PE

Signal transduction

19q13.2

10F12

PSG7

pregnancy specific beta-1-glycoprotein 7

several PE

Signal transduction

19q13.2

10C11

PSG7

pregnancy specific beta-1-glycoprotein 7

several PE

Signal transduction

19q13.2

16F9

RPL41

ribosomal protein L41

several PE

Transcription/Translation/Modifi

12q13

18B9

RPS11

ribosomal protein S11

one PE case

Transcription/Translation/Modifi

19q13.3

13C9

RPS24

ribosomal protein S24

one PE case

Transcription/Translation/Modifi

10q22-23

4C8

RPS6KC1

ribosomal protein S6 kinase, 52kDa, polypeptide 1

severe PE

Transcription/Translation/Modifi

1q41

10C8

rRNA 28S

Human 28S ribosomal RNA gene

one PE case

RNA gene

8q21.1-q21.2

6G8

S100P

S100 calcium binding protein P

one PE case

Cell cycle

4p16

5D3

SMARCC1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

one PE case

Structure de la chromatine

3p23-21

8A2

SRP9

signal recognition particle 9kDa

one PE case

Transport

1q42.13

5E10

UCP2

uncoupling protein 2 (mitochondrial, proton carrier)

one PE case

Mitochondrial metabolism

11q13

8C3

VIM

vimentin

one PE case

Structural protein

10p13

5H2

WBSCR1

Williams-Beuren syndrome chromosome region 1 EIF4H

one PE case

Transcription/Translation/Modifi

7q11.23

14E4

WBSCR16

Williams-Beuren syndrome chromosome region 16

one PE case

Transcription/Translation/Modifi

7q11.23

12C8

YWHAZ

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

Terms/PE

Signal transduction

8q23.1

4B6