Figure 1

Alignments of putative EH1 motifs in a) Homeobox and b) Paired box domain containing proteins, subdivided by domain partners and orientation, with representative non-bilaterian sequences included. Alignments were derived from meme searches, as described in text. Conserved aromatic residues (FHYW) are coloured white on a red background ('a' in the consensus). Conserved aliphatic residues (ILV), black on a yellow background. ('I' in the consensus) Conserved big residues (EFHIKLMQRWY) blue on a light yellow background ('b' in the consensus). Conservation is calculated over the full alignment of sequences in figures 1 and 2. The figure was produced using the Chroma program [41]. Gene names are standard HUGO Gene Nommenclature Committee, flybase or wormbase symbols where available, otherwise accessions for their respective databases. When available Uniprot protein accessions are also given [42], along with the starting residue of the motif.