Table 1 Cell cycle-related genes significantly regulated by butyrate.

TC265170

Aurora kinase A (AURKA)

0.17

0

TC266385

Aurora kinase B (AURKB)

0.18

0

TC278061

Aurora-A kinase interacting protein (AURKAIP1)

0.19

0

TC281252

BUB1 budding uninhibited by benzimidazoles 1 homolog (BUB1)

0.10

0

TC281450

BUB1 budding uninhibited by benzimidazoles 1 homolog beta (BUB1B)

0.06

0

TC280420

CDC28 protein kinase regulatory subunit 2

0.02

0

TC292959

CDC2L1

0.04

0

TC293208

CDC45 cell division cycle 45-like

0.09

0

TC278776

Cell division cycle 2, G1 to S and G2 to M (CDC2)

0.12

0

TC285500

Cell division cycle 25A (CDC25A)

0.11

0

TC271610

Cell division cycle 25B isoform 3

0.14

0

TC294713

Cell division cycle 2-related

0.16

0

TC278478

Cell division cycle and apoptosis regulator 1

0.17

0

TC294633

Cell division cycle associated 2 (CDCA2)

0.08

0

TC292945

Cell division cycle associated 8

0.17

0

TC263741

Cell division cycle protein 20 homolog (p55CDC)

0.10

0

CK975861

Centromere protein F (350/400kD)

0.06

0

TC261165

Centromere protein-A (CENP-A)

0.09

0

TC267900

Centromeric protein E (CENP-E protein)

0.11

0

TC279457

CHK1 checkpoint homolog

0.16

0

TC293183

Chromatin assembly factor 1 subunit A (CAF-1)

0.20

0

TC268367

Chromobox protein homolog 5

0.10

0

TC297649

Chromodomain helicase DNA binding protein 3

0.14

0

TC265382

Chromosome condensation protein G

0.06

0

TC262952

Cyclin A2

0.17

0

TC265945

Cyclin B1 (CCNB1)

0.06

0

TC278429

Cyclin B2 (CCNB2)

0.22

0

TC262075

Cyclin G1

0.07

0

TC262855

Cyclin-dependent kinase 4

0.15

0

TC265450

Cyclin-dependent kinase inhibitor 2C

0.22

0

TC278545

Cyclin-dependent kinases regulatory subunit 1 (CKS-1)

0.09

0

TC284317

Defective in sister chromatid cohesion homolog 1

0.06

0

TC290880

Deoxythymidylate kinase (thymidylate kinase) (LOC506946)

0.15

0

TC273170

Discs large homolog 7 (DLG7)

0.22

0

TC265245

DNA directed RNA polymerase III polypeptide D

0.12

0

TC284361

DNA helicase (Blooms syndrome protein, RecQ protein-like 3)

0.11

0

TC267167

DNA mismatch repair protein Msh3 (mut S homolog 3)

0.24

0

TC278497

DNA polymerase epsilon p17 subunit gene

0.03

0

TC279954

DNA polymerase, alpha 2 (70kD subunit)(POLA2)

0.11

0

CK945922

DNA repair and recombination protein RAD54-likex

0.06

0

TC282404

DNA repair protein RAD51 homolog 1

0.11

0

TC290487

E2F transcription factor 4

0.11

0

TC282153

Establishment of cohesion 1 homolog 2

0.13

0

TC265789

Extra spindle poles like 1 (ESPL1)

0.08

0

TC291293

flap structure-specific endonuclease 1 (FEN1)

0.18

0

TC266990

G-2 and S-phase expressed 1

0.23

0

TC270253

GAJ protein (MND1)

0.07

0

TC292293

General transcription factor IIIC, polypeptide 2, beta 110kDa

0.24

0

BG688435

H/ACA ribonucleoprotein complex subunit 4 (Dyskerin, DKC1)

0.11

0

TC269917

Helicase, lymphoid-specific

0.13

0

TC267482

Histone deacetylase 8

0.15

0

TC276662

Histone H2A.Z

0.08

0

TC272233

Huntingtin interacting protein 2 (HIP2)

0.25

0

TC267608

Inner centromere protein

0.11

0

TC279078

Katanin p80 (KATNB1)

0.16

0

TC295304

Kinesin family member 11

0.23

0

TC294618

Kinesin family member 14

0.20

0

TC267353

Kinesin family member 20A

0.12

0

TC260588

Kinesin-like protein KIF22

0.09

0

TC291455

Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1)

0.07

0

TC278220

Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin)

0.19

0

TC266372

Kinetochore associated 2

0.15

0

TC284307

Lamin B1 (LMNB1)

0.05

0

TC277820

MAD2 mitotic arrest deficient-like 1

0.07

0

TC288554

Max interacting protein 1 (MXI1)

12.55

0

TC261106

MCM4 (CDC21 homolog) DNA replication licensing factor

0.14

0

TC264981

Minichromosome maintenance deficient 3 (MCM3)

0.10

0

TC277221

Minichromosome maintenance deficient 5 (MCM5, CDC46 homolog)

0.17

0

TC265572

Minichromosome maintenance deficient 6 (MCM6)

0.09

0

TC263581

Minichromosome maintenance protein 2

0.14

0

TC290639

Minichromosome maintenance protein 3 associated protein

0.16

0

TC293069

Mitotic spindle associated protein p126, MAP126

0.04

0

TC298939

M-phase phosphoprotein 1 (mitotic kinesin-like protein, MPHOSPH1)

0.13

0

TC260429

MutS homolog 6

0.21

0

TC266513

NEK2 (NIMA-related protein kinase 2)

0.13

0

TC278195

Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1)

0.19

0

TC279654

Nucleolar and spindle associated protein 1

0.08

0

TC274682

Nucleolin

0.10

0

TC293949

Origin recognition complex subunit 1

0.23

0

TC281941

PDZ-binding kinase (PBK)

0.15

0

TC278800

pescadillo homolog 1, containing BRCT domain (PES1)

0.17

0

TC289876

Proliferating cell nuclear antigen (PCNA)

0.09

0

TC263003

Proliferation-associated 2G4

0.16

0

TC276620

Proteasome (prosome, macropain) 28 subunit, alpha

0.21

0

TC260258

Proteasome subunit, beta type 8 (PSMB8)

0.14

0

TC292683

Protein C20orf172 (C20orf172)

0.06

0

TC300533

Protein regulator of cytokinesis 1

0.07

0

TC279370

Protein regulator of cytokinesis 1 (PRC1)

0.11

0

TC282034

RAD51 associated protein 1 (RAD51AP1)

0.21

0

TC280581

Replication factor C (activator 1) 3 (RFC3)

0.19

0

TC265859

Replication factor C (activator 1) 4 (RFC4)

0.03

0

TC263936

Ribonucleoside-diphosphate reductase M2 chain (RRM2)

0.17

0

TC275004

Scaffold attachment factor B2

0.20

0

TC266542

Sin3 associated polypeptide p30 (SAP30)

0.22

0

TC282970

SMC4 structural maintenance of chromosomes 4-like 1 (SMC4L1)

0.13

0

TC290192

Spindle pole body component 24 (kinetochore protein Spc24)

0.09

0

TC281963

Spindle pole body component 25 (kinetochore protein Spc25)

0.14

0

TC279153

Topoisomerase (DNA) II binding

0.05

0

TC278044

Transcription elongation regulator 1

0.09

0

TC281731

Transducin (beta)-like 1X-linked receptor 1 (TBL1XR1)

0.08

0

TC277942

Ubiquitin-conjugating enzyme E2 C (Ubiquitin-protein ligase C)

0.14

0

TC280380

Wee1-like protein kinase

0.16

0

TC279802

XPMC2 prevents mitotic catastrophe 2 homolog

0.21

0