Figure 4

Location of polymorphic regions mapped to the MAP genome. The outermost ring is the nucleotide position from the origin of replication, while the green ring is the percentage of GC nucleotides. The innermost rings represent the ORFs that were identified as variably present (log ratio < -1.2) in at least one of the mycobacterial genomes (blue) as well as ORFs conserved in all of the isolates examined (black). ORFs that are annotated as mobile genetic elements are colored red. The numbers adjacent to polymorphic sequences correspond to the LSP numbers listed in Table 2. The circular genome MAP was generated with the software program Microbial Genome Viewer [50].