Table 1 Status level definitions. Status level definitions accompanying each gene symbol verified by RGST.

H1

Rat gene that has a human ortholog with an established human HUGO symbol that is identical with at least one of the rat gene symbols from RGD, Ensembl, or NCBI. The human HUGO symbol is used as a rat gene symbol reference.

H2

Rat gene that has a human ortholog with an established human HUGO symbol that is inconsistent with rat gene symbol(s) from RGD, Ensembl, and NCBI. The human HUGO symbol is used as a rat gene symbol reference.

R1

Rat gene that does not have a human HUGO symbol as a reference. RGD symbol available, and in agreement with both Ensembl and NCBI (if available). The RGD symbol is used as a rat gene symbol reference.

R2

Rat gene that does not have a HUGO symbol as a reference. RGD symbol available, but in disagreement with Ensembl and/or NCBI. The RGD symbol is used as a rat gene symbol reference.

R3

Rat gene that does not have a human HUGO symbol as a reference. No RGD symbol available. No mouse MGI symbol available. Identical symbol in Ensembl and NCBI, or symbol only present in one of these two datasets; this symbol is used as a rat gene symbol reference.

M1

Rat gene that does not have a human HUGO symbol as a reference. No RGD symbol available. Mouse MGI symbol identical with at least one symbol from Ensembl or NCBI; this symbol is used as a rat gene symbol reference.

M2

Rat gene that does not have a human HUGO symbol as a reference. No RGD symbol available. Mouse MGI symbol is used as a rat gene symbol reference.

IL

Rat gene that cannot be categorized in any of the above status levels. Reserved for manual consideration.

IS

Where a gene symbol is not in accordance with rat gene nomenclature rules, its status is given the suffix IS.