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Table 4 TFBS in promoters of genes expressed in prostate cancer are conserved between Human and Opossum

From: Evolutionary conservation of zinc finger transcription factor binding sites in promoters of genes co-expressed with WT1 in prostate cancer

Gene

 

WT1

 

EGR1

 

SP1

 

AP2

 
 

Conserved betweena

#Cons. sitesb

Total#c

#Cons. sitesb

Total#c

#Cons. sitesb

Total#c

#Cons. sitesb

Total#c

EGR1

H-Op

1

8

2

10

1

7

PA

1

GATA2

H-Op

1

8

0

1

PA

5

0

3

IGFBP2

H-Op

0

3

1

6

1

7

NP

NP

NPY

H-Op

0

9

0

2

0

4

1

5

SOX4

H-Op

0

2

2

2

0

3

NP

NP

TFAP2C

H-Op

NP

NP

1

4

2

8

PA

1

WT1

H-Op

1

7

0

3

2

6

PA

4

  1. a H-Op = Conservation between human and opossum.
  2. b Number of conserved sites: PA = only partial alignment of promoters as constructed by MultiPipMaker [79], NP = no TFBS in human promoters as predicted by the MatIspector [75], and 0 = TFBS not conserved.
  3. c Total number of predicted sites is based on sites in human promoters.
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BMC Genomics

ISSN: 1471-2164

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