Figure 5From: High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors: Four cases of homozygous deletions of the CDKN2A geneAmplification of MYCN. (A) Representative tumors with simple continuous amplicons amplified. (B) Tumors with complex rearrangements. (C) The sample marked with an asterisk from the A panel in more detail. The figure shows how precisely the amplification borders can be defined using this technique. (D) The common region of amplification in tumors and cell lines. No genes other than MYCN were found in all cases with amplification.Back to article page