Figure 1From: Integrating transcriptomics and proteomics to show that tanshinone IIA suppresses cell growth by blocking glucose metabolism in gastric cancer cells Effects of TIIA on cell growth and proliferation of AGS cells. (A) Growth curves show a dosage-dependent pattern of growth inhibition after TIIA treatment for 72 hr. All TIIA treatment conditions had significant effects on AGS cell growth (p < 0.0001, Wilcoxon Signed-Rank Test). Cell indexes of AGS cells were measured by an RTCA DP® system, expressed as mean ± SD of three replications. (B) Colonies of AGS cells were stained by crystal violet (purple-colored dots) after TIIA treatment. Control conditions exhibit many colonies, while IC50 TIIA conditions have produced almost no colonies. (C) TIIA significantly reduces the number of AGS colonies (*p < 0.05, **p < 0.01, Student’s t-Test) in a dosage-dependent manner. Histogram values are expressed as mean ± SD from three replications.Back to article page