Skip to main content

Table 3 D. discoideum developmental genes lacking orthologs in the A. subglobosum lineage a

From: Comparative genome and transcriptome analyses of the social amoeba Acytostelium subglobosum that accomplishes multicellular development without germ-soma differentiation

Gene b

Product

Mutant information c

Involved in cell fate-determination

  tagA (DDB_G0293002)

ABC transporter B family protein, serine protease

Multiple tips in mound (partial KO); Aberrant fruiting body morphology (KO)

Involved in stalk-cell diversification

  rtaA* (DDB_G0271852)

Lipid-translocating exporter family protein

Expressed in PstU cells (lacZ fusion)

  warA* (DDB_G0291075)

Putative homeobox transcription factor

Development arrests at slug stage, decreased prespore cell differentiation, and increased PstO cell differentiation (KO)

Involved in terminal differentiation

  expl7 (DDB_G0288331)

Expansin-like protein

Aberrant culminant morphology (OE)

  rsc12* (DDB_G0277871)

Unknown

Aberrant culmination (KO)

  1. aOnly those related to morphogenesis and cell differentiation are listed.
  2. bUnique genes are asterisked. Parentheses indicate DDB_G ID.
  3. cPhenotypes of disruptants (KO) and overexpressors (OE), and product localization (lacZ fusion) were extracted from the dictyBase phenotype summary [27].