Figure 2

Exome INDEL call set analysis per individual. a. To characterize the exome INDEL length distribution in individuals we calculated the density of exome INDELs of different lengths in each individual. Shorter INDELs are generally common with a strong bias towards INDEL lengths that are a multiple of 3 (inframe). The INDEL density for the HuRef and YanHuang exome are also shown for reference. Deletions are shown with negative length. b. To characterize the allele frequency distribution in individuals we calculated the exome INDEL density in each individual across 7 logarithmic allele frequency bins. The results confirm that most of the exome INDELs in an individual are common (>10%), but most individuals harbor a small number of extremely rare exome INDELs (i.e. singletons).