Figure 7

Genes with altered expression that potentially are controlled by transcription factors regulated during the transformation. (A) List of genes regulated from the brown adipose phase to the transition phase, which have consensus putative response elements for nuclear receptor subfamily 1, group H, member 3 (NR1H3) and v-myc avian myelocytomatosis viral oncogene homolog (MYC). (B) Subcellular localization of differentially expressed genes from the transition phase to the white adipose phase that have consensus putative response elements for NR1H3, MYC, B-cell lymphoma 6 (BCL6), estrogen receptor 1 (ESR1), krüppel-like factor 4 (KLF4) and v-rel reticuloendotheliosis viral oncogene homolog A (RELA). Green nodes indicate down-regulated genes in the white adipose phase as compared to the transition phase and red nodes indicate up-regulated genes in the white adipose phase as compared to the transition phase. The corresponding gene names are listed in Additional file 10: Table S7.