Fig. 4

The gene ontology and pathway enrichment results at indicated time points for NTP treatment for 1 min and 3 min. The Biological Processes BP, Molecular Function MF and Cellular Components CC terms were performed for GO enrichment analysis and the KEGG, REACTOME and WikiPathways databases were performed for pathway enrichment analysis of each differential group genes. The statistical test was Enrichment/Depletion two-side hypergeometric test, and the Benjamini and Hochberg false-discovery rate was set to 0.05. Terms with up/down regulated genes are shown in red/green, respectively. The color gradient shows the gene proportion of each cluster associated with the term. Equal proportions of the two clusters are represented in gray. The resulting corrected p values are included in the network visualization by the size of nodes.