Fig. 9From: Comparative genomic and phenomic analysis of Clostridium difficile and Clostridium sordellii, two related pathogens with differing host tissue preferencePossible mechanisms of acid adaptation. Several C. sordellii genes could be utilized to sequester protons and improve the internal and surrounding pH. a The expected contributions of urease, glutamate decarboxylase, and arginine deiminase to increasing the cytoplasmic pH under acidic conditions are depicted. b The NhaA Na+/H+ antiporter is expected to improve alkaline adaptationBack to article page