Fig. 3

Differential expression between the SGs, cultured KCs and HaCats. a The heat map panel to the left shows the expression of cytokeratins in different samples. Annotations for cytokeratins in the panel to the right for the gene expression on different layers and tissue types (orange) are based on Takahashi et al. [19], for the status in activation cycle (green) are based on Freedberg et al. [1], and for the protein expression in five cell types (blue) are based on Human Protein Atlas, HPA [21]. According to HPA, white denotes no data, gray means not detected (primary cell types) or with negative intensity (HaCaT), and red represents varying protein levels according to the intensity of the colour. SG, Split-thickness skin graft; EKC, early passage keratinocyte; LKC, late passage keratinocyte; HCTP, HaCaT. b The heat map shows the expression of collagens in different samples