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Table 5 aDifferentially expressed genes with fold change ≥2 in mammary gland of cows fed 5 % safflower oil (on dry matter bases)

From: Transcriptome adaptation of the bovine mammary gland to diets rich in unsaturated fatty acids shows greater impact of linseed oil over safflower oil on gene expression and metabolic pathways

 

bSFO day+28 compared with day-14

SFO day+28 compared with day+7

Genes

cFC

log2FC

P-value

FDR

P-value

FC

log2FC

P-value

FDR

P-value

RNASE1

3.664

1.874

2.33E-07

0.0008

3.280

1.713

7.21E-07

0.0018

UCP2

2.362

1.240

1.91E-06

0.0021

2.839

1.505

7.88E-09

8.79E-05

SPADH1

2.104

1.073

1.45E-05

0.0098

2.191

1.132

4.28E-06

0.0037

FBP2

6.302

2.656

2.52E-05

0.0111

4.973

2.314

4.26E-05

0.0127

LBP

2.318

1.213

2.87E-05

0.0122

2.052

1.037

0.0003

0.0437

DPP10

−2.308

−1.207

5.29E-05

0.0177

−2.110

−1.077

0.0004

0.0520

ANGPTL4

2.131

1.091

0.0001

0.0326

2.247

1.168

2.73E-05

0.0092

ACE2

3.061

1.614

1.28E-07

0.0008

-

-

-

-

HPGD

2.159

1.110

1.77E-07

0.0008

-

-

-

-

MROH2B

−2.784

−1.477

1.06E-05

0.0084

-

-

-

-

TIEG2

2.115

1.080

1.49E-05

0.0098

-

-

-

-

SCGB1D

2.112

1.079

4.70E-05

0.0168

-

-

-

-

OLR1

3.168

1.664

0.0004

0.0650

-

-

-

-

ALDH1L2

2.001

1.001

0.0004

0.0651

-

-

-

-

ENSBTAG00000016127

-

-

-

-

3.659

1.871

1.29E-06

0.0024

SLC17A9

-

-

-

-

2.543

1.346

4.08E-06

0.0037

MMP19

-

-

-

-

2.206

1.141

1.75E-05

0.0065

ENSBTAG00000000414

-

-

-

-

2.316

1.213

2.09E-05

0.0075

SCIN

-

-

-

-

2.510

1.328

2.31E-05

0.0081

IL17RB

-

-

-

-

2.217

1.149

4.57E-05

0.0127

STATH

-

-

-

-

−2.030

−1.022

0.0002

0.0393

ISG15

-

-

-

-

−2.676

−1.420

0.0006

0.0640

MX1

    

−1.964

−0.974

0.0009

0.0843

  1. aOnly genes with fold change values ≥2.00 are shown. Complete list of differentially expressed genes are shown in Additional file 6a-b. No genes were significantly differentially expressed between day+7 as compared to day-14. bSFO (safflower oil), day-14 (control period), day+7 (7 days of supplemental feeding with 5 % safflower oil), day+28 (28 days of supplemental feeding with 5 % safflower oil). cFC (Fold change)
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BMC Genomics

ISSN: 1471-2164

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