Table 3 Human genes absent from CyCMV Mauritius
From: A novel strain of cynomolgus macaque cytomegalovirus: implications for host-virus co-evolution
Gene | CyCMV Ottawa/RhCMV 68.1 Homologue | Functiona | Effect of deletion on viral growth kineticsb | Family |
|---|---|---|---|---|
RL2 | −/− | - | no effect |  |
RL3 | −/− | - | no data |  |
RL4 | −/− | - | no effect |  |
RL5 | −/− | - | no data | RL11 |
RL6 | −/− | - | no effect | RL11 |
RL7 | −/− | - | no data |  |
RL8 | −/− | - | no data |  |
RL9 | −/− | - | no effect |  |
RL10 | −/− | - | no effect | RL11 |
RL11 | cyRL11/rh05 | IgG Fc-binding glycoprotein | no effect | RL11 |
RL12 | −/− | Putative membrane glycoprotein | no effect | RL11 |
RL13 | −/− | Putative membrane glycoprotein | no effect |  |
RL14 | −/− | - | no data |  |
UL1 | −/− | - | no data | RL11 |
UL2 | −/− | - | modest effect | RL11 |
UL3 | −/− | - | no effect |  |
UL4 | −/− | - | no effect | RL11 |
UL5 | −/− | - | no effect | RL11 |
UL8 | −/− | - | no effect | RL11 |
UL10 | −/− | Temperance factor in retinal tissueb | no effect | RL11 |
UL12 | −/− | - | modest effect |  |
UL15 | −/− | - | no effect |  |
UL16 | −/− | Membrane glycoportein involved in inhibiting Natural Killer cell cytotoxicity | no effect |  |
UL17 | -/rh35 | 7-transmembrane glycoprotein | no effect | Â |
UL18 | −/− | MHCI homologue putative membrane protein | no effect | UL18 |
UL22 | −/− | - | no data |  |
UL39 | −/− | - | no effect |  |
UL40 | -/rh67 | Membrane glycoptrotein | no data | Â |
UL58 | −/− | - | no data |  |
UL59 | −/− | - | no effect |  |
UL60 | −/− | - | required for replication |  |
UL61 | −/− | - | no data |  |
UL62 | −/− | - | no effect |  |
UL63 | −/− | - | no data |  |
UL64 | −/− | - | no effect |  |
UL65 | −/− | - | modest effect |  |
UL66 | −/− | - | no data |  |
UL67 | −/− | - | no effect |  |
UL68 | −/− | - | no data |  |
UL80.5 | -/rh109.1 | Capsid Scaffold Protein | no data | Core |
UL81 | −/− | - | no data |  |
UL101 | −/− | - | required for replication |  |
UL106 | −/− | - | no data |  |
UL107 | −/− | - | no data |  |
UL108 | −/− | - | no data |  |
UL109 | −/− | - | modest effect |  |
UL110 | −/− | - | no effect |  |
UL118 | -/rh151 | - | no effect | Â |
UL124 | -/rh156.2 | Membrane glycoprotein latent protein | no data | Â |
UL125 | −/− | - | variable critical effect |  |
UL127 | −/− | - | no data |  |
UL129 | −/− | - | no effect |  |
UL143 | −/− | Inhibits Natural Killer cell cytotoxicity | modest effect |  |
UL142 | −/− | Putative membrane protein | no data |  |
UL139 | −/− | Putative membrane glycoprotein | no data |  |
UL138 | −/− | Putative membrane protein | no data |  |
UL137 | −/− | - | no data |  |
UL136 | −/− | Putative membrane protein | no data |  |
UL135 | −/− | Putative secreted protein | no data |  |
UL134 | −/− | - | no data |  |
UL133 | −/− | Putative membrane protein | no data |  |
UL148A | −/− | Putative membrane protein | no data |  |
UL148B | −/− | Putative membrane protein | no data |  |
UL148C | −/− | Putative membrane protein | no data |  |
UL148D | −/− | Putative membrane protein | no data |  |
UL149 | −/− |  | no data |  |
UL150 | −/− | Putative Secreted Protein | no data |  |
IRS1 | −/− | Immediate early membrane protein & transcriptional activator/blocks protein kinase R mediated repression of translation | no data |  |
US4 | −/− | - | no effect | US22 |
US5 | -/rh183 | - | no data | Â |
US6 | -/rh185 | Putative membrane glycoprotein/Inhibits TAP mediated ER peptide transport | no data | Â |
US7 | −/− | Membrane glycoprotein | no effect | US6 |
US8 | /-rh187 | MHCI binding Membrane glycoprotein | no effect | US6 |
US9 | −/− | Membrane glycoprotein involved in cell to cell spread | no effect | US6 |
US10 | −/− | membrane glycoprotein/Delays trafficking of MHCI | no effect | US6 |
US15 | −/− | Putative multiple transmembrane protein | no effect | US6 |
US16 | −/− | Temperance factor and Putative multiple transmembrane protein | no effect | US12 |
US25 | −/− | - | no effect | US12 |
US27 | −/− | Virion Envelope Glycoprotein/Potentiates CXCR4 receptorc | no effect |  |
US33 | −/− | - | no effect | GPCR |
US34 | −/− | Putative secreted protein | no effect |  |
US34A | −/− | Putative membrane protein | no effect |  |