Fig. 3

Gene ontology analysis of categorized gene promoters. a The 140 gene promoters selected (see text) were classified in “Strong” (>10-fold increase over the genome average reads), “Moderate” (5 to 10-fold increase), and “Weak” (2 to 5-fold change). b Each group of genes was subjected to Gene Ontology analysis and terms with p-value <0.01 were selected. Only the highest scores are presented in the Table. NSOT, No Significant Ontology Term can be assigned to this gene subset. c Genes were grouped according to the potency of Crz1 recruitment and the corresponding transcriptional data in response to alkaline pH stress (fold-change) were extracted from five independent datasets and presented as box plots for each dataset. Because the large dispersion of higher values and to facilitate comparison between plots the upper whisker is not shown fully in some graphs. Datasets used are: Casado et al. [34]; Casamayor et al. [35]; Causton et al. [1]; Serrano et al. [33]; and Viladevall et al. [4]. Data correspond in all cases to the response after 10 min of exposure to pH 8.0, except in reference [33], which correspond to 15 min to pH 8.2. Only genes with valid data in at least 2 datasets were used for the plots