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Table 3 Distribution of CDSs annotated as antimicrobial resistance genes

From: Comparative genomics of Clostridium bolteae and Clostridium clostridioforme reveals species-specific genomic properties and numerous putative antibiotic resistance determinants

  ARDB Number of clusters and orphans C. bolteae 90A5 C. bolteae 90A7 C. bolteae 90A9 C. bolteae 90B3 C. bolteae 90B7 C. bolteae 90B8 C. clostridioforme 90A1 C. clostridioforme 90A3 C. clostridioforme 90A4 C. clostridioforme 90A6 C. clostridioforme 90A8 C. clostridioforme 90B1
class A beta-lactamase blaCLO1 2 1 1 1 1 1 1 1 1 1 1 1 1
class B beta-lactamase metallo-enzymes 4 1 2 1 1 1 1 2 1 2 2 2 1
class C beta-lactamase Amp C and Penicillin Binding Protein 1 1 1 1 1 1 1 1 1 1 1 1 1
class D beta-lactamase Amp D (oxa type) 2 1 1 1 1 1 1 1 1 1 1 2 1
Teicoplanin, Vancomycin VanRA 4   2      1 1 1 1 3 1
VanSA 1        1 1 1 1 1 1
VanD 2        2 2 2 2   2
VanSD 1        1 1 1 1   1
VanXD 1        1 1 1 1   1
VanRD 2        1 1 1 1   1
Vancomycin VanHB 2 1 1 1 1 1 1 1 1 1 1 2 1
VanRB 2 1 1 1 1 1 1 1 1 1 1 2 1
VanB 1            1  
VanSB 1            1  
VanWB 1            1  
VanXB 1            1  
VanYB 2            2  
VanSC 1            1  
VanRE 1   1 1 1         
VanG 1 1 1 1 1 1 1 1 1 1 1 1 1
VanRG 3 2 2 2 2 2 2 1 1 1 1 1 1
VanYG 1 1 1 1 1 1 1       
VanUG 3 2     1        
Teicoplanin VanZ 4 2 3 1 1 2 1 2 2 2 2 2 2
Lincomycin LnuA 3 1 1 1 1 1 1 1 1 1 2 1 2
Macrolides ErmB 1          1   1  
Macrolide-Lincosamide- Streptogramin (efflux pumps) MacB 1 6 8 7 7 6 6 6 6 6 6 5 6
MefA 1 3 2 4 4 3 3 3 3 3 4 3 3
MsrA/MsrB 5 3   3 3 3 3       
Lsa 1   1         1   1
ABC transporter (efflux pumps) VgaA 1 1 1 1 1 1 1 1 1 1 1 1 1
Tirc 1 1 1 1 1 1 1 1 1 1 1 1 1
CcmA 6   2      2 3 3 2 4 3
Streptogramin_A Chloramphenicol VatB 2 1 1 1 1 1 1 1 1 1 1 1 1
chloramphenicol CAT 3 1     1 2   1 1 1 1 1
linezolide Cfr 2 1 1   2 1   1 1 1 1 1 1
Rifampicin Arr 1 1 1 1 1 1 1       
Metronidazole Nim 1 1 1 1 1 1 1 1 1 1 1 1 1
Trimethoprim Dfra20 1 1 1 1 1 1 1 1 1 1 1 1 1
Dfra 1           1   
Aminoglycosides Aac6ie 2             2
Aad9ib 1     1         
Ant6ia 3   1      1 2 1 2   1
Aph3iiia 1         2   1   1
Apha 3 3 3 3 3 3 3 3 3 3 3 3 3
Tetracycline Tet40 1     1       1   
TetO 1 1 1 1 1 1 1      1  
TetW 1        1 1   1   1
Tet32 1          1 1   
Bacitracin BacA 3 1 1 2 2 1 1 1 2 2 1 1 2
BcrA 1 2 3 4 4 2 3 3 4 4 3 4 5
Multidrug resistance efflux pump Blt 1   1           
AcrB 3 2 2 2 2 2 2 3 3 3 3 3 3
  1. aBroad annotation