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Fig. 2 | BMC Genomics

Fig. 2

From: Insights into the ancestral organisation of the mammalian MHC class II region from the genome of the pteropid bat, Pteropus alecto

Fig. 2

Comparative gene maps of bat MHC-II region (centre) against human, horse and pig MHC-II regions. Red arrows represent classical MHC-II genes, green arrows represent non-classical MHC-II genes, blue arrows represent flanking MHC-II region genes and purple arrows represent essential AP genes [37]. The areas highlighted in purple represent the antigen-processing (AP) cluster. ψ represents putative pseudogenes. The direction and orientation of the MHC-II regions relative to the telomere centromere are shown. The human, horse and pig gene maps were adapted from the Ensembl annotation

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