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Fig. 4 | BMC Genomics

Fig. 4

From: Impact of blood collection and processing on peripheral blood gene expression profiling in type 1 diabetes

Fig. 4

QPCR and NanoString arrays in matching PBC samples processed using the PAXgene and Tempus system. The expression of lymphocyte-signature genes (COX6C, COX7B, LSM3, RPS24, and RPL31), and genes previously shown to be changed in T1D or at-risk patients (COX6C, COX7B, LSM3, RPS24, RPL31, COMMD6, SUB1, and UQCRB; see Fig. 2) were measured by QPCR and/or NanoString arrays (a-h). Microarray, QPCR and/or NanoString arrays gave similar results, and NanoString array data showed the least amount of variation between samples. *P < 0.05; **P < 0.005 in PAXgene vs. Tempus-processed samples, two-tailed Wilcoxon matched-pairs signed rank test

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BMC Genomics

ISSN: 1471-2164

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