Fig. 3
From: The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia
Receiver operating characteristics (ROC) analysis. a, b ROC curves of differentially expressed genes between AML and ALL, the plot shows higher AUC with the PA method. c Genes were selected from the literature based on putative targets of 17-oncology drugs used in clinic for the AML and ALL treatment. d The gene targets of 47 approved and investigational oncology compounds, which had high efficacy towards primary AML and ALL samples based on in-house ex vivo drug testing data. e Leukemia specific marker genes from microarray based published studies. f Cluster of differentiation (CD) marker genes. The PA protocol provided constantly higher RPKM values for the target genes in all comparisons