Fig. 1

Hierarchical clustering of Jak gain-of-function and Stat loss-of-function mutants show separation by gene and stage of the embryo. (a) Differentially regulated genes were clustered by Pearson’s correlation complete distance separation. (b) Overlaps between Stat92E ^mat- and Stat92E ^06346/+ embryos were determined and suggest that a large number of genes are regulated stage-specifically