Deciphering the genetic regulation of peripheral blood transcriptome in pigs through expression genome-wide association study and allele-specific expression analysis

Table 5 Correspondence between sets of eQTL- and ASE-SNPs detected in this study and gene sets that were differentially expressed (DE) in the blood of pigs studied for levels of immunity traits

	IL-2^a	IL-10^b	Phagocytosis^c	CD4-CD8 + ^d
DE genes [3]	850	733	1195	52
DE local-associated genes	69	64	107	5
DE distant-associated genes	56	47	74	0
DE genes with ASE signal	48	29	61	7

^aProduction of IL-2 after in vitro stimulation of total blood with phorbolmyristate acetate (PMA) and ionomycin for 48 h
^bProduction of IL-10 after in vitro stimulation of total blood with PMA and ionomycin for 48 h
^cQuantification of phagocytosis capacity via in vitro tests on total blood
^dCD4-CD8+ lymphocyte count measured by flow cytometry

ISSN: 1471-2164