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Fig. 2 | BMC Genomics

Fig. 2

From: Transcriptome analyses of immune tissues from three Japanese frogs (genus Rana ) reveals their utility in characterizing major histocompatibility complex class II

Fig. 2

Amino acid alignment of selected MHC-IIB variants from three Japanese Rana species (R. japonica- Raja, R. ornativentris- Raor, and R. t. tagoi- Rata) spanning from exons 1 to 4. All β1 domain (exon 2) sequences from these species were allocated to one of three supertypes (ST-D, ST-E and ST-F), indicated on the right. Positive selected codon sites detected using omegaMap are shaded in grey. Amphibian peptide binding residues [18] are indicated by coloured boxes that represent pocket residues (P4, P6,P7 or P9). For supertyping analyses, the first three pocket residues were excluded due to absent sequence information in some other species (position 9, 11, and 13). Sequences were also included for human-HosaDQB (Genbank accession M33907.1), and transcriptome sequences obtained from R.pirica- Rapi and L. catesbeianus-Lica. **The Raor-09 variant is identical at the amino acid level with Rata-04, Raor-01 and Raor-02 variants

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BMC Genomics

ISSN: 1471-2164

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