Fig. 7

FuSpot Visualization of THRB-AZIN2 False Positive Fusion Junction Using FusionMap Supporting Reads. FuSpot’s visualization of the putative THRB-AZIN2 fusion gene claimed by FusionMap when given the BEERS data set [25]. Each read seen here was reported by the FusionMap fusion detector tool when run on the above-mentioned data set. To begin, FusionMap identified 4 supporting reads. Inspection in FuSpot revealed that the second and fourth reads were reverse complemented copies of the first and third reads respectively, diminishing the amount of reliable supporting evidence. This evidence alone is insufficient to draw a meaningful conclusion about the validity of the fusion