Fig. 8

Detection of enhancer RNAs from Start-seq data. a Metaplot describing position-specific enrichment over full window median probability of Start-seq signal in a 4 kb window around summits of ATAC-seq peaks that overlap with gene TSSs (Promoters, green), overlapping FlyLight enhancers (Enhancers, red), or overlapping neither feature (Non-overlapping, blue), along with randomly assorted genomic regions (Random, purple). b Metaplot of sense (red) or antisense (blue) Start-seq signal mapping in a 500 nt window around enhancer-associated nuTSSs. c Representative browser window examples of enhancer-associated nuTSSs oriented in the sense (top) or antisense (bottom) direction relative to the gene containing the enhancer