Transcriptional analysis of liver from chickens with fast (meat bird), moderate (F1 layer x meat bird cross) and low (layer bird) growth potential

Table 5 Pathways and associated genes identified as enriched by KEGG of the 155 DE genes between meat birds, crossed and layer birds

	Mean CPM^a (± SEM)			Direction^c	Fold Change^b
Gene name	Meat bird (n = 6)	Cross (n = 6)	Layer (n = 6)	Direction^c	M&L	M&C	C&L
FoxO signalling pathway
CCND2	183 ± 13	126 ± 9	79 ± 3	↑	2.3	1.4	1.6
CCNG2	348 ± 16	193 ± 15	104 ± 16	↑	3.4	1.8	1.9
CCKN1B	52 ± 1	60 ± 2	73 ± 2	↓	1.4	1.1	1.2
CDKN2B	364 ± 56	116 ± 18	13 ± 4	↑	28.2	3.1	9.0
INSR	86 ± 1	106 ± 4	131 ± 4	↓	1.5	1.2	1.2
Fructose and mannose metabolism
PFKFB2	25 ± 2	31 ± 1	39 ± 1	↓	1.6	1.2	1.3
PFKL	296 ± 18	235 ± 7	170 ± 13	↑	1.7	1.3	1.4
TSTA3	49 ± 4	31 ± 1	21 ± 2	↑	2.4	1.6	1.5

^aMean CPM gene expression values are ‘counts per million’ transcripts to normalise for varying depth of sequence among samples
^bFold change comparisons: M&L = Meat bird and Layer; M&C = Meat bird and Cross; L&C = Layer and Cross
^cDirection of regulation: ↑ Meat bird upregulated (meat bird > cross > layer); ↓ Meat bird downregulated (meat bird < cross < layer)

ISSN: 1471-2164